ea0063gp59 | Acromegaly and GH | ECE2019
Chiloiro Sabrina
, Giampietro Antonella
, Bianchi Antonio
, Bima Chiara
, Frara Stefano
, Mirra Federica
, Donfrancesco Federico
, Fleseriu Cara Maria
, Fleseriu Maria
, Giustina Andrea
, Laura De Marinis
, Pontecorvi Alfredo
Purpose: Osteopathy is an emerging complication of acromegaly characterized by increased bone turnover, deterioration in bone microarchitecture and high risk of vertebral fractures (VFs). In somatostatin analog (SSA)-resistant patients (pts), Pegvisomant (PegV) and Pasireotide LAR (Pasi) are used for acromegaly treatment, but their effect on skeletal health is still not defined.Methods: In a longitudinal international multicenter study, we evaluated inci...